Jennifer Jason Leigh was born Jennifer Lee Morrow on the 5th of February 1962 in Hollywood, California to Hollywood star Vic Morrow and Hollywood screenwriter Barbara Turner. She grew up in Hollywood and at the age of 14, she trained under Lee Strasberg. At the age of 16, she already had her Screen Actors Guild membership after appearing in an episode of the television series Baretta. After Baretta she was seen in several movies made for television, including The Best Little Girl in the World.

Then in 1980, Jennifer Jason Leigh debuted for film in the movie, Eyes of a Stranger. Two years after, she was in the teen hit comedy film Fast Times at Ridgemont High. The film starred future Hollywood stars such as Nicolas Cage, Forest Whitaker, Anthony Edwards, Sean Penn, Judge Reinhold, Eric Stoltz and Phoebe Cates.

In 1985, Jennifer Jason Leigh appeared in the film Flesh & Blood. In the film, she played the role of a rape victim. The following year, she was in the film The Hitcher. In 1989, she landed the role of a young woman on the brink of insanity in the film Heart of Midnight.

Then in 1990 she appeared in the Last Exit to Brooklyn as Tralala, a tough prostitute. Then still in 1990 she landed another role as a prostitute in the film Miami Blues, where she played opposite Alec Baldwin. The following year, she was in the film Rush, as a narcotics cop who eventually became a junkie.

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